2024-03-16
Invasive neuronal tract tracing is prohibited in very large or endangered animals, particularly marine mammals like dolphins. Scientists from Germany and Italy propose diffusion-weighted imaging as a feasible alternative, even in brains fixed in formalin for extended periods. The results of employing the Constrained Spherical Deconvolution algorithm on diffusion data from fixed bottlenose dolphin brains, demonstrated a successful identification of fiber patterns within voxels, shedding light on cetacean neuroanatomy. These findings underscore the importance of short-term post-mortem fixation for preserving tissue integrity and highlight the significance of preprocessing techniques in mitigating imaging artifacts, ultimately enhancing our understanding of cetacean brain structure.
Invasive neuronal tract tracing is prohibited in very large or endangered animals, particularly marine mammals like dolphins. Scientists from Germany and Italy propose diffusion-weighted imaging as a feasible alternative, even in brains fixed in formalin for extended periods. The results of employing the Constrained Spherical Deconvolution algorithm on diffusion data from fixed bottlenose dolphin brains, demonstrated a successful identification of fiber patterns within voxels, shedding light on cetacean neuroanatomy. These findings underscore the importance of short-term post-mortem fixation for preserving tissue integrity and highlight the significance of preprocessing techniques in mitigating imaging artifacts, ultimately enhancing our understanding of cetacean brain structure.
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Last update: Mar 16, 2024
